Friday - March 18, 2022
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- Game 13 @ 1:00 PM
- LCU Rip Griffin Center
- #4 Northwest Florida - 50
- #13 South Plains - 54
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- Game 14 @ 3:00 PM
- LCU Rip Griffin Center
- #5 Wabash Valley - 59
- #12 Western Nebraska - 70
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- Game 15 @ 5:00 PM
- LCU Rip Griffin Center
- #3 Georgia Highlands - 79
- #19 Hutchinson - 71
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- Game 16 @ 7:00 PM
- LCU Rip Griffin Center
- #6 Southern Idaho - 49
- #11 Trinity Valley - 75